Protein-Protein and Domain-Domain Interactions

Protein-Protein and Domain-Domain Interactions

Author: Pandjassarame Kangueane

Publisher: Springer

ISBN: 9789811073472

Category: Medical

Page: 207

View: 451

This book illustrates the importance and significance of the molecular (physical and chemical) and evolutionary (gene fusion) principles of protein-protein and domain-domain interactions towards the understanding of cell division, disease mechanism and target definition in drug discovery. It describes the complex issues associated with this phenomenon using cutting edge advancement in Bioinformatics and Bioinformation Discovery. The chapters provide current information pertaining to the types of protein-protein complexes (homodimers, heterodimers, multimer complexes) in context with various specific and sensitive biological functions. The significance of such complex formation in human biology in the light of molecular evolution is also highlighted using several examples. The chapters also describe recent advancements on the molecular principles of protein-protein interaction with reference to evolution towards target identification in drug discovery. Finally, the book also elucidates a comprehensive yet a representative description of a large number of challenges associated with the molecular interaction of proteins.
Protein-Protein and Domain-Domain Interactions
Language: en
Pages: 207
Authors: Pandjassarame Kangueane, Christina Nilofer
Categories: Medical
Type: BOOK - Published: 2018-02-16 - Publisher: Springer

This book illustrates the importance and significance of the molecular (physical and chemical) and evolutionary (gene fusion) principles of protein-protein and domain-domain interactions towards the understanding of cell division, disease mechanism and target definition in drug discovery. It describes the complex issues associated with this phenomenon using cutting edge advancement
Protein-protein Interactions and Networks
Language: en
Pages: 212
Authors: Anna Panchenko, Teresa M. Przytycka
Categories: Science
Type: BOOK - Published: 2010-04-06 - Publisher: Springer Science & Business Media

The biological interactions of living organisms, and protein-protein interactions in particular, are astonishingly diverse. This comprehensive book provides a broad, thorough and multidisciplinary coverage of its field. It integrates different approaches from bioinformatics, biochemistry, computational analysis and systems biology to offer the reader a comprehensive global view of the diverse
Protein-protein Interactions and Networks
Language: en
Pages: 212
Authors: Anna Panchenko, Teresa M. Przytycka
Categories: Science
Type: BOOK - Published: 2009-08-29 - Publisher: Springer

The biological interactions of living organisms, and protein-protein interactions in particular, are astonishingly diverse. This comprehensive book provides a broad, thorough and multidisciplinary coverage of its field. It integrates different approaches from bioinformatics, biochemistry, computational analysis and systems biology to offer the reader a comprehensive global view of the diverse
A Computational Study of the Role of Conserved Domains in Protein Interactions [microform]
Language: en
Pages: 314
Authors: Doron Betel
Categories: Science
Type: BOOK - Published: 2005 - Publisher: Library and Archives Canada = Bibliothèque et Archives Canada

Complex organisms that are capable of inter-cellular communication and occupy various ecological niches are believed to evolve through the generation of novel cellular pathways. The myriad of processes in a cell are facilitated by proteins that form the building blocks of complex pathways through a set of carefully orchestrated interactions
Computational Prediction of Protein-Protein Interaction
Language: en
Pages: 56
Authors: Ranjan Kumar Barman, Anirban Mukhopadhyay
Categories: Science
Type: BOOK - Published: 2011-12 - Publisher: LAP Lambert Academic Publishing

Protein-protein interactions are extremely valuable towards protein functions and cellular processes or we can say that protein-protein interactions play an important role in living cells. Therefore, if we can control the interactions between proteins, as a result, we can control some functionality of cells. Main functionality of a protein is