Protein-Protein and Domain-Domain Interactions

Protein-Protein and Domain-Domain Interactions

Author: Pandjassarame Kangueane

Publisher: Springer

ISBN: 9789811073472

Category: Medical

Page: 207

View: 184

This book illustrates the importance and significance of the molecular (physical and chemical) and evolutionary (gene fusion) principles of protein-protein and domain-domain interactions towards the understanding of cell division, disease mechanism and target definition in drug discovery. It describes the complex issues associated with this phenomenon using cutting edge advancement in Bioinformatics and Bioinformation Discovery. The chapters provide current information pertaining to the types of protein-protein complexes (homodimers, heterodimers, multimer complexes) in context with various specific and sensitive biological functions. The significance of such complex formation in human biology in the light of molecular evolution is also highlighted using several examples. The chapters also describe recent advancements on the molecular principles of protein-protein interaction with reference to evolution towards target identification in drug discovery. Finally, the book also elucidates a comprehensive yet a representative description of a large number of challenges associated with the molecular interaction of proteins.
Protein-Protein and Domain-Domain Interactions
Language: en
Pages: 207
Authors: Pandjassarame Kangueane, Christina Nilofer
Categories: Medical
Type: BOOK - Published: 2018-02-16 - Publisher: Springer

This book illustrates the importance and significance of the molecular (physical and chemical) and evolutionary (gene fusion) principles of protein-protein and domain-domain interactions towards the understanding of cell division, disease mechanism and target definition in drug discovery. It describes the complex issues associated with this phenomenon using cutting edge advancement
Protein-protein Interactions and Networks
Language: en
Pages: 212
Authors: Anna Panchenko, Teresa M. Przytycka
Categories: Science
Type: BOOK - Published: 2008-09-10 - Publisher: Springer

The biological interactions of living organisms, and protein-protein interactions in particular, are astonishingly diverse. This comprehensive book provides a broad, thorough and multidisciplinary coverage of its field. It integrates different approaches from bioinformatics, biochemistry, computational analysis and systems biology to offer the reader a comprehensive global view of the diverse
Modular Protein Domains
Language: en
Pages: 524
Authors: Giovanni Cesareni, Mario Gimona, Marius Sudol, Michael Yaffe
Categories: Science
Type: BOOK - Published: 2006-03-06 - Publisher: John Wiley & Sons

Since the full functionality of any given protein can only be understood in terms of its interaction with other, often regulatory proteins, this unique reference source covers all relevant protein domains, including SH2, SH3, PDZ, WW, PTB, EH, PH and PX. Its user-oriented concept combines broad coverage with easy retrieval
Protein-protein Complexes
Language: en
Pages: 401
Authors: Martin Zacharias
Categories: Science
Type: BOOK - Published: 2010 - Publisher: World Scientific

Given the immense progress achieved in elucidating protein-protein complex structures and in the field of protein interaction modeling, there is great demand for a book that gives interested researchers/students a comprehensive overview of the field. This book does just that. It focuses on what can be learned about protein-protein interactions
Protein-Protein Interactions
Language: en
Pages: 488
Authors: Weibo Cai, Hao Hong
Categories: Science
Type: BOOK - Published: 2012-03-30 - Publisher: BoD – Books on Demand

Proteins are indispensable players in virtually all biological events. The functions of proteins are coordinated through intricate regulatory networks of transient protein-protein interactions (PPIs). To predict and/or study PPIs, a wide variety of techniques have been developed over the last several decades. Many in vitro and in vivo assays have